The Ultimate Guide to Yasmin Pill

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Yasmin pill is a hormonal contraceptive used to prevent pregnancy, and improve symptom of premenstrual dysphoric disorder. It also helps treat acne in women above 14 years who are in their initial phase of menstrual periods.

Yasmin birth control pills come in two packages, one consisting of 21 pills and the other containing 28. The 21 pack contains only active pills, while the 28 includes 21 active pills and seven placebo pills. The active tablets comprise both estrogen and progestin. Meanwhile, the inactive pills or placebo pills do not contain any hormones as they are only there to help people keep with their routines.


Yasmin pills are contraceptive medication that only helps in preventing pregnancy. It does not protect you from sexually transmitted diseases like HIV, Gonorrhea, Chlamydia, etc.

Yasmin pill is a prescription-based drug that a certified doctor must prescribe after carefully assessing the patient’s medical condition.

How do Yasmin pills work?

It contains two types of medicines – Drospirenone and Ethinylestradiol. Drospirenone is a progestin (female hormone) that prevent pregnancy by stopping the ovary from releasing the egg and getting fertilized by sperm. Ethinylestradiol is also a female hormone (a form of synthetic estrogen) that helps maintain a regular menstrual cycle. It is usually helpful for menopausal women by preventing mood swings, hot flushes and night sweats by fulfilling required estrogen deficiency.

Benefits of Yasmin Pills

When taken as per your doctor’s guidelines, Yasmin pills can help you prevent unwanted pregnancy. In addition to that, it comes with several health benefits, such as:

  • It allows you to skip or shorten menstrual periods
  • It provides relief from PMS symptoms such as cramps, nausea and acne
  • It decreases the endometrium thickness resulting in lighter periods and lowering the risk of endometrial cancer

How to Use Yasmin Pills?

Yasmin pills should be taken as prescribed by your doctor, preferable after a meal at night with water.

You can take it on the first of the start of the menstruation or the first Sunday after the onset of a menstrual period.

Starting from the Day 1 of Menstruation

Your doctor may prescribe you one Yasmin active pill daily at the beginning of the first menstrual cycle. You must take one active pill daily for 21 days consecutively, followed by one inactive pill from the 22nd day to the 28th day. Then again, start taking a new pack of Yasmin after finishing the last inactive or placebo pills.

It’s essential to take your pills regularly as missing a dose increases your chances of getting pregnant.

If you miss one active pill, take it as soon as you remember and continue taking the next pills as per the schedule. If you miss two active pills in the last week of the active pills, skip your placebo pills and start a new pack of active pills after finishing the current ones. If you cannot use a new package, you must use backup non-hormonal pills for seven days, then take the missed pills. Patients on a different dosage of Yasmin must consult their doctor in case of missed dosage.

 Starting from First Sunday

You can start your first Yasmin active pill on the first Sunday of the beginning of your first menstrual cycle. You need to take one active pill each day for 21 days, followed by one placebo pill from 22nd to 28th. If you are on the 21 pills pack, stop taking the active pills after 21 days for seven days. The contraceptive benefit of the drugs only after you take the active pills for the first seven consecutive days.

You must start your following regimen on the same day of the week that you begin your first regimen. In this case, the day is Sunday. You must take the active pills the next day after finishing your placebo pills. If you are on a 21-day pack, you must wait for seven days before restarting your course. Make sure not to miss any pill. It’s better if you maintain a calendar for the same.

Switching from a different birth control pill

You must start the Yasmin pill the day you started the other contraceptive pill. Don’t take Yasmin pills with your current brand pills, as it could cause significant side effects.

Switching from other forms of contraceptive

If you switch from a vaginal ring or a transdermal patch, start taking Yasmin pills on the set date of your next application of the above methods.

If you are taking the injection, start Yasmin pills on your next injection.

If you are switching from an intrauterine contraceptive or an implant, start Yasmin pills on the day of removal.

Withdrawal bleeding while being on Yasmin pills

You may experience withdrawal bleeding within three days of your last active pill. Meaning if your active pills end on the 21st of the month, you may expect a withdrawal bleeding within the 24th of the said month. You may also experience breakthrough bleeding while on Yasmin active tablets; in such cases, you should continue taking the pills. Such bleeding is usually temporary and most likely won’t cause any complications.

However, if the bleeding persists or worsen, you should consult your doctor as soon as possible.

While Yasmin pills are highly effective in stopping pregnancy when taken according to your healthcare provider. However, a lack of withdrawal bleeding may signify a possible pregnancy in rare cases, especially when you miss one or more active tablets and take them on a day later than prescribed. If you miss your first period, you must visit your doctor to take appropriate diagnostics. The risk of pregnancy usually increases when you miss the active tablets.


Yasmin pills may induce severe vomiting or diarrhea, which significantly lowers its absorption rate in your body. In such cases, you must take additional contraceptive methods. If you have vomited within 3-4 hours of taking the pill, that will be considered a missed dose.

Side-effects of Yasmin Pills

Some common side-effects of Yasmin pills include nausea, vomiting, headache, mood changes, weight gain, lower sex drive, tiredness, breast tenderness and changes in the menstrual cycle.

While these common side-effects subside on their own, you may consult your doctor if they persist or worsen.

Although they rarely happen, Yasmin pills may cause serious side effects in some people. It includes:

  • Vision problems
  • Sudden vision loss
  • Chest pain or feeling of heavy chest
  • Shortness of breath
  • Slurred speech
  • Sudden onset of severe headache, numbness or weakness
  • Blood in cough
  • Dark urine or clay-colored stools
  • Upper stomach pain
  • Pain or warmth in legs
  • Pain in jaw or shoulder
  • Sweating
  • Swelling on hands, feet or ankles
  • Severe migraines

If you have any symptoms mentioned above, seek medical attention right away.

Drug Interactions of Yasmin Pills

When taken with Yasmin pills, certain drugs can diminish its contraceptive potential and increase breakthrough bleeding. Some of these drugs or herbal products include:

  • Phenytoin
  • Barbiturates
  • Carbamazepine
  • Oxcarbazepine
  • Rifampin
  • Topiramate
  • Bosentan
  • Felbamate
  • Griseofulvin
  • Supplements containing St. John’s wort

Tell your doctor about your current medications before asking for a Yasmin pills prescription.

Some drugs and substances may increase the plasma concentration of Yasmin pills.

For instance, co-administrating Yasmin pills or combined oral contraceptives (COCs) with atorvastatin can increase AUC values for EE value by 20 per cent. Similarly, taking ascorbic acid or acetaminophen pills may also increase plasma EE concentration.

A mild to modern increase in plasma concentration can happen when taking COCs with:

  • Azole antifungals such as ketoconazole, voriconazole, fluconazole, itraconazole, etc.
  • Verapamil
  • Macrolides like clarithromycin and erythromycin
  • Diltiazem
  • Grapefruits

When taken with HIV or HCV protease inhibitors of Non-nucleoside reverse transcriptase inhibitors, Yasmin pills can significantly increase or decrease the plasma concentrations of estrogen and progestin in some cases.

Taking Yasmin pills may increase the metabolism of certain other medications, which negates the efficiency of the other medicines. When taken with lamotrigine, Yasmin pills can induct lamotrigine glucuronidation. This results to reduce the seizure control effects of the drug. Inform your doctor beforehand so that they may adjust the dosage of lamotrigine if necessary.

Yasmin pills may also increase or weaken the plasma concentration of CYP2C19 substrates (omeprazole and voriconazole) and CYP1A2 substrates (theophylline and tizanidine).

Women with thyroid hormone replacement therapy may need an increased dosage as Yasmin pills may increase the serum concentration of thyroid-binding globulin.

Contraceptive pills such as Yasmin can also alter the results of specific laboratory tests such as lipids, glucose tolerance, coagulation factors and binding proteins.


Can I purchase Yasmin pills without a prescription?

Yasmin pills are prescription-based drugs that you can only purchase with a valid prescription from a certified practitioner.

Do Yasmin pills cause hair loss?

No, Yasmin is an anti-androgenic contraceptive pill containing two hormones- oestrogen and progestin. Contrarily, Yasmin can reduce the actions of androgen on your hair follicles.

Androgens are present in small amounts in both men and women. However, the concentration is lower in women compared to men. Some women’s hair follicles are susceptible to androgen. Contraceptives containing male androgen hormones can cause hair loss in such women. However, Yasmin pills do not contain androgenic hormones.

Can you take Yasmin pills after childbirth or abortion?

Postpartum mothers (who do not breastfeed) or women who had an abortion after a second trimester can take Yasmin pills after four weeks of the postpartum or abortion date. Taking the medications earlier increases the risk of thromboembolism. It’s advised to use additional contraception methods for seven days of starting your Yasmin pills.

Can combining Yasmin pills with antibiotics increase contraceptive failure?

There has been a report of pregnancy while taking hormonal contraceptives with antibiotics such as Amoxicillin, ampicillin, griseofulvin, metronidazole, and tetracycline. However, clinical studies do not show any sign of signifying antibiotics (except rifampin) decreasing the effects of hormonal contraceptives.