What is Etizolam?
Etizolam is a thieno diazepine that is chemically identified with benzodiazepine (BDZ) drug class. It was patented in 1972, was then approved for medical use in 1983. It varies from BDZs in having a benzene ring replaced with a thiophene ring. It is an agonist at GABA-A receptors and has properties that can manage memory loss (amnesic), anxiety (anxiolytic), convulsions (anticonvulsant), sleep (hypnotic), and skeletal muscle relaxation. It is used with less tolerance and addiction potential.
What is Etizolam used for?
It is used either on its own or other medications to treat major depressive disorders, social anxiety issues, obsessive-compulsive disorders, depression, and panic disorders. It can also be utilized to treat psychosomatic illnesses like migraine, irritable bowel syndrome, and hypertension. Apart from stress, it can also help manage cervical spondylosis, Lumbar disease, and Cancer pain. Etizolam is also a short-term treatment option for disturbed sleep (insomnia).
How does Etizolam work?
It normally works like other benzodiazepine drugs. The mediation focuses on increasing the gamma-aminobutyric acid (GABA) level in the brain, thus easing nerve impulses and increasing neurotransmitters. Etizolam works by binding itself to the GABA receptors in the central nervous system. Their inhibition of the GABA pathway prompts an increase in GABAergic transmission, thus improving GABA-initiated Cl currents.
This aids in calming the activated nerve pathways and thus treats anxiety, seizures, and convulsions. Etizolam likewise applies its binding effects on the alpha and gamma units to help treat sleep deprivation.
How long does Etizolam take to kick in?
It is well absorbed in the gastrointestinal tract; it rapidly floods the brain and arrives at the peak levels approximately 30 minutes to two hours after ingestion.
How long does Etizolam last?
It has a plasma half-life of 3.5 hours, while alpha-Hydroxyetizolam, which is its active metabolite, has a half-life of more than 8 hours. The half-life is a significant mark of the duration of activity. The impacts of Etizolam reach their peak at around 3 to 4 hours and can last somewhere in the range of 6 to 8 hours total. After this time period, it is metabolized by the liver and excreted through the kidneys in the form of urine and feces. Taking it on an empty stomach with lots of water helps the drug kick in at a quicker rate.
What is the dosage of Etizolam?
It is sold online and is shipped to clients/customers as bulk etizolam powder or pressed tablets. It is accessible in strengths of 0.5mg, 1mg, 2mg, and 5mg. The dose of the drug depends upon what the treatment is for and its strength. Normally, tablets of 0.5mg-0.25mg are recommended three times every day for a maximum duration of 12 weeks.
- For insomnia, 1mg-2mg is prescribed once every day.
- For panic disorders, 0.5mg of the tablet is taken twice every day.
- For anxiety disorders, 0.25mg-0.5mg is recommended twice daily, with the total dose not exceeding 3 mg per day.
Etizolam vs. Xanax -which is better?
Both Xanax and Etizolam are utilized for the treatment of anxiety and a sleeping disorder. While Xanax is really a benzodiazepine, Etizolam is a benzodiazepine analog. Etizolam displays the properties of Benzodiazepines yet is really a Thienodiazepine. It is accessible in Japan, India, and a couple of other countries yet is not legal in the USA. Xanax has been approved by the USA and is a common anxiolytic that is used there.
What is Etizolam’s legal status in Australia?
Being a benzodiazepine analog, you can buy Etizolam in Australia only through a prescription. It is utilized principally for anxiety issues and sleep disorders. In Australia, it is characterized as a Schedule IV medication under the Poisons Standard of June 2018. It implies that the purchase of this medication is just permitted from an authorized local or over-the-counter pharmacy on a valid prescription from a duly affirmed doctor to issue such medicines. The drug is illegal when bought in the city from a non-authorized supplier.
What are the precautions to keep in mind before you buy Etizolam online in Australia?
Before you purchase it from any Australian online pharmacy, it is important to remember that
- The drug is available in various colors. Etizolam 1mg tablets are dark blue and come in foil strips; Etizolam 2mg tablets come in a pink shade.
- It is critical to purchase it from a genuine pharmacy to guarantee its authenticity.
- Avoid utilizing tablets if you notice any sign of tampering or pilferage on the package. If the tablets look damaged or yellowed, don’t use them.
Do generic Etizolam in Australia come with any side effects?
Etizolam, in general, has some side effects- generic and branded. Its use can increase prolactin levels in the blood and possibly bring about spontaneous production of breast milk, interruptions in the menstrual cycle, and infertility in women, hypogonadism, and erectile dysfunction in men. Its long-haul use can cause blepharospasm (abnormal twitches or contractions of eyelids). In very rare cases, the drug was found to cause skin lesions. Etizolam with liquor or other CNS-active substances can have disastrous aftereffects prompting overdose and genuine clinical issues like death or coma. Etizolam, similar to all benzodiazepine-class drugs, has a high potential for addiction and can cause serious physical withdrawal symptoms with prolonged use.
Etizolam drug interactions:
Being a benzodiazepine analog, it may lead to decreased mental and motor function when combined with alcohol. The results of the interaction between the two are usually depression, feelings of drowsiness, confusion, and loss of coordination.
When combined with anticoagulants, it can lead to a decrease in its metabolism. This can lead to an overdose in the system.
The risk and the severity of side effects associated with either medication increases when combined.
With anticholinergic medications
When combined with anticholinergic medication, it increases the CNS (Central Nervous System) depressive activities of the medication.
When combined with antihistamines, it can lead to an increase in the sedative activities of the medication