Cialis vs. Viagra- Which is better in 2022?

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Cialis (Tadalafil) and Viagra (Sildenafil citrate) are oral pills used for treating conditions of impotence (Erectile Dysfunction), such as the inability to achieve or maintain an erection and benign prostatic hyperplasia (BPH). They belong to a class of drugs known as phosphodiesterase-5 (PDE5) inhibitors that increase the blood flow to blood vessels, causing an erection.

How Cialis and Viagra Works?

In medical terms, a penile erection is referred to the engorgement of the male sexual organ with blood. Generally, when a person experiences sexual stimulation, the body produces nitric oxide and releases it in the male organ. The nitric oxide then actives an enzyme called guanylate cyclase, which further makes cyclic guanosine monophosphate (cGMP). The cGMP decides the amount of blood the blood vessels pump and flush from the male sexual organ.

An enzyme called phosphodiesterase-5 (PD5) can destroy the cGMP in the body, which inhibits an individual from achieving an erection. As a PDE5 inhibitor, Cialis and Viagra prevent the destruction of cGMP and allow it to stay in the system longer. The longer cGMP stays in the body; the longer one can achieve an erection.

Cialis or Viagra? Which one is better for erectile dysfunction (ED)?

Although Viagra has a well-known reputation for treating ED. However, Cialis has also captured a significant market share as an alternative drug. Customers usually prefer Cialis over Viagra as they have more prolonged effects and are comparatively well-tolerated than Viagra. However, Cialis also stays in the system for a long time to increase drug interactions (lowering or intensifying the drug potency) for people on other drugs.

Though people always wonder which one is better than the two, the answer is not that simple. In general, both work equally well for treating erectile dysfunction in men. However, the effectiveness of the drugs works differently in different individuals. It depends upon the severity of ED and the amount of sexual stimulation one experiences. You have to understand that Cialis and Viagra can only help in cases where an individual is feeling the sexual stimulation but unable to achieve an erection. It does not help a person get an erection when no stimulation is involved.

As we have already established that both Cialis and Viagra work in the same efficiency, now to help with your purchase decision, we have divided some crucial characteristics of both drugs into sections.

Duration of effects

Cialis (Tadalafil) works longer than Viagra, earning the name “the weekend pill.” While Viagra stays effective for 4 to 5 hours, a single dose of Cialis can make you last for up to 36 hours. Although it lasts longer, that does not indicate you will have an erection through the period. It will only happen when you are sexually stimulated.

In terms of effectiveness, Viagra is reported as 84 percent effective in achieving an erection, while Cialis is at 81 percent. Although Viagra has a bit higher effect, most men prefer Cialis due to its longer effect.

Speed of work

Generic Viagra starts working within 30 minutes of consumption. However, its effects may get diminished after a high-fat meal, which is one of the downsides of Viagra. That’s why Viagra works best when consumed on an empty stomach.
You can experience the effects of Cialis within 16 to 45 minutes, and it reaches its peak within 1 hour of consumption. The best part is you can have Cialis with food. Although it is preferred to take in an empty stomach, having a meal before or after does not diminish its effect considerably.

Cost and Availability

The cost of Cialis and Viagra are generally the same. However, the price may differ as per your resident county. Besides, both are prescription-based drugs, meaning you have to show a prescription to buy Cialis online or even Viagra, in that matter. You can also buy Viagra or Cialis at your nearby pharmacy via a prescription.

Retail Price of Cialis and Viagra in the US (price may vary among countries)

A 30 days course of Cialis 2.5mg or 5mg oral tablet may cost you around $380, while the 10mg Cialis will cost $2186 for 30 tablets.

A 50 mg Viagra containing 30 tablets costs around $2446 (approx. $82 per unit). The price is almost the same for Viagra 100 mg as well.

The exact price you pay for Viagra or Cialis depends on your resident country, insurance plan, and the platform you purchase it from. Most health insurance companies do not cover Viagra and Cialis, so you have to keep in mind that as well. However, you may get them covered in your health plan if you have certain medical conditions. We recommend you confirm it with your insurance provider.

On the other hand, purchasing through a pharmacy might cost you more as you have to pay the full price. In contrast, you can get the same at a discount rate if you buy Cialis or Viagra online.

Generic versions of Viagra and Cialis can cost half as much of their name-brand counterparts. Make sure to talk to your doctor to prescribe you generic versions of Cialis (Tadalafil) or Viagra (Sildenafil). Above all, make sure to purchase them from a reputed online pharmacy to avoid fake products.

Dosage

Viagra is taken on an as-needed basis, preferably of a 50 mg dose. Although it starts working within 30 minutes, you will see its maximum effects within 1 hour of consumption. The results will last best within 4-5 hours of consumption.

Cialis is available on both a daily and as-needed basis. Generally, your doctor might prescribe you a single dose of Cialis 2.5 mg or 5 mg everyday use. While you don’t have to follow the daily routine for ED, it is advised to take Cialis daily for treating BPH. Do not take more than a single Cialis within 24 hours.

Cialis as-needed dosages are available in 10 mg and 20 mg. These doses work for a long time, up to 72 hours, compared to the lower dosages. Considering the severity of the condition, your doctor may ask you to take 10 mg of Cialis daily, but that is hardly required. It is better to take the Cialis 10mg dose every 72 hours.

Side-effects of Cialis and Viagra

Cialis

Common side-effects of Cialis include:
• Facial flushing
• Headache
• Nausea
• Flu-like symptoms such as runny nose
• Diarrhea
• Stomach upset

Cialis may cause serious side-effects such as low blood pressure, blurred vision, change in color perception, abnormal ejaculation, and priapism (erection lasting for four hours causing damage to the male sexual organ).
If you see such symptoms, seek immediate medical attention.

The likelihood of getting side effects from Cialis is relatively lower than Viagra (not mean it won’t happen).
Based on clinical trials, men taking 5mg of Tadalafil (generic name of Cialis), around 11 percent of them witness headache, 4 percent stomach discomfort, 3 percent back pain, 2 percent nasal congestion & flushing, and 1 percent myalgia (muscle pain) & pain in limb.

Similarly, in 10 mg Tadalafil, 11 percent of people experience headache, 8 percent stomach discomfort, 5 percent back pain, 4 percent myalgia, and 3 percent nasal congestion and flushing.

Viagra

Around 15 percent of people taking Viagra experience some form of side effects.

Some common side effects of Viagra include:
• Facial flushing
• Headaches
• Stomach pain
• Nasal congestion
• Nausea
• Dizziness
• Rash
• UTI
• Diarrhea
• Inability to differentia between colors blue and green
• Priapism

Fixed Dosage: Headache and facial flushing are pretty common in Viagra as around 16-28 percent of people experienced headaches during clinical trials when in Viagra 25mg-100mg. About 10-18 percent of people experienced flushing and stomach discomfort. Similarly, around 11 percent of people experienced vision changes in 100 mg of Viagra.

Flexible Dosage: Meanwhile, the rate of headache & dyspepsia (stomach discomfort) is reduced to 16 & 10 percent, respectively, when taking viagra on an as-needed basis. Similarly, all the other symptoms of side-effects are also reduced to (1 in 100) in flexible dosage.

Drug interactions with Cialis and Viagra

Both Cialis and Viagra are PDE5 inhibitors, meaning they similarly interact with other drugs. However, Cialis stays in the system longer, so taking some medications simultaneously as Cialis or viagra can increase or reduce the levels of the drug in the blood.

Avoid taking Cialis and Viagra with:

• Nitrates such as amyl nitrite, butyl nitrite, isosorbide mononitrate, isosorbide dinitrate, and nitroglycerin.
• High blood pressure or alpha-blockers such as terazosin, tasmulosin, doxazosin, prazosin, etc.
• Certain HIV drugs
• Oral antifungal drugs
• Antibiotics
• PAH drugs
• Stomach acid drugs containing magnesium hydroxide or aluminum hydroxide
• Epilepsy drugs
• Other ED drugs

The list of drug interactions is not complete; make sure to inform your doctor about your medical history and drugs you are currently or planning to take. Also, tell your doctor if you have a recent heart-related surgery or any heart episode or taking any heart-related medications. Taking Viagra and Cialis under such circumstances can be extremely dangerous.